3.19.26

50 startups transforming industries with physical AI

After decades of promise, autonomous systems and robotics are moving from labs to factory floors and households — powered by breakthroughs in AI and hardware.

The convergence of AI and robotics is reshaping the physical world across every imaginable industry, from defense and manufacturing to healthcare and consumer experiences. At our very first Robotics Day in San Francisco, we gathered founders, builders, and researchers in intelligent automation and robotics. The experts, alongside our investment team, explored the fundamental shift from software-only AI systems to embodied intelligence — machines that can see, understand, and act in dynamic environments. This transformation represents one of the most significant technological inflections of our generation, with applications spanning autonomous vehicles, defense systems, agriculture, and beyond. 

In our latest research, the robotics market is experiencing explosive growth driven by three key factors: breakthrough advances in AI foundation models that enable better perception and decision-making, dramatic reductions in hardware costs, and acute labor shortages across critical industries. By 2035, it’s expected that there will be over 2.5 billion robots worldwide, but this figure understates the true opportunity — as robots become more capable and general-purpose, they’ll create entirely new markets rather than simply automating existing workflows.

The companies leading this revolution share common characteristics: 

  • World-class technical teams combining robotics, AI, and systems engineering expertise
  • Focus on high-value, repeatable use cases that justify the complexity of deploying physical systems
  • Deep partnerships with customers who can provide the real-world data necessary for continuous improvement

Most importantly, these companies are building full-stack solutions that integrate hardware, software, and AI rather than betting on pure software or commoditized hardware alone.

Companies shaping the future of robotics and autonomous systems

While the industry has yet to reach the “ChatGPT moment” for robotics, advancements in autonomous systems and robotics have already reached commercial success, influencing our everyday lives. As we surveyed the landscape, two companies — Waymo and Anduril Industries — were undeniable leaders serving as clear examples of what’s possible for founders to achieve as they turn physical AI research into new applications, transforming their given industries.

In total, we’ve identified 50 of the most promising private companies — the innovators we believe will define the next decade of physical AI. These names represent the vanguard of intelligent automation across several key categories:

Autonomous vehicles

The race to autonomous transportation continues to accelerate, with applications ranging from long-haul trucking to last-mile delivery to ridesharing.

Waymo

Leading robotaxi service with commercial deployment in major cities throughout the U.S.

Applied Intuition

Simulation and validation platform powering AV development

Wayve

AI driver software to equip a range of vehicles with autonomous capabilities

Waabi

Next-generation self-driving technology leveraging generative AI

Nuro

Custom-built autonomous delivery vehicles

Climate and agriculture

Robotics is addressing the agricultural labor crisis while also improving sustainability.

Carbon Robotics

AI-powered weeding robots reducing herbicide use

Orchard

Autonomous platform for orchard management

Seneca

AI-powered autonomous fire suppression drones

Upside Robotics

Autonomous field robots for agricultural tasks

Consumer robotics

By bringing intelligent automation into everyday life, consumer robotics is paving the way for a future where robots operate more widely amongst humans.

Figure

Humanoid robots for commercial applications

Matic

Autonomous home cleaning robots

Sunday AI

Robotic household care that handles everyday tasks

Zipline

Autonomous drone delivery at scale

1X

General-purpose humanoid robots

Coco

Largest fleet of autonomous sidewalk delivery robots

The Bot Company

Household robotics for various tasks

Defense

Defense is being reimagined by these companies offering autonomous systems for ensuring national security.

Anduril Industries

Advanced autonomous defense systems, including drones, submarines, and AI-powered software platforms

Neros Technologies

Mass-produced attritable first-person view drones

NODA AI 

Orchestration platform for multi-domain autonomous systems

Auterion

AI-enabled autonomous systems for defense for autonomous drone operations

Saronic Technologies

Autonomous surface vessels for maritime defense

Shield AI

AI pilot software and autonomous aircraft for military aviation

Skydio

Autonomous drones and docking systems with advanced AI for public safety

Breaker Industries

Voice-command orchestration for autonomous systems 

Generalized foundation models

These companies are building the AI brains that will power the next generation of robots.

World Labs

Spatial intelligence to build foundation models for AI capable of understanding and generating 3D worlds

Dyna Robotics

Embodied AGI for general-purpose robots

Generalist

Foundation models for robotic manipulation

Perceptron AI

Base perceptive models for robotics

Physical Intelligence

Foundation models for robotic manipulation

Skild AI

Scalable robot learning platform

Eka Robotics

Robotics that masters physics through self-supervised learning and sim-to-real reinforcement learning. 

Health and life sciences

In the healthcare and life sciences industry, these precision robotics companies are transforming the delivery of care.

Periodic Labs

AI-powered scientists and autonomous labs to accelerate materials discovery in the physical sciences

Mendaera

Focalist — an FDA-cleared handheld robotic system for assistance in high-precision medical procedures

Radical AI

Chemical manufacturing accelerating materials R&D through AI and robotics labs

Medra

AI-powered autonomous robotics system for life sciences labs

Industrial robotics

From reimagining manufacturing to automating warehouses, these companies are leading the way in industrial robotics.

Bedrock Robotics

Autonomous systems for industrial environments

Cobot

Mobile collaborative robot and platform

DroneDeploy

Aerial intelligence for industrial sites

Mind Robotics

AI-driven industrial manipulation

Mytra

Warehouse automation and robotics

Tutor Intelligence

Industrial AI and robotics training

Sereact

Robotics intelligence for autonomous operations

Field AI

Autonomy software for robots navigating dynamic unstructured environments

Anybotics

Autonomous legged robots for industrial applications

RobCo

Full-stack platform for autonomy

Robotics infrastructure

Last, but certainly not least, these companies are the foundational tools enabling the entire ecosystem.

Zeromatter

High-performance simulation platform for building, testing, and training autonomous systems

Foxglove

Full-stack observability platform for visualization and debugging tools for robotics

Point One Navigation

Precision positioning for autonomous systems

Voxel51

Visual AI and computer vision data platform

Theseus

AI-powered GPS for military drones using vision-based technology and sensor fusion

The next generation of physical AI

The leaders on this list represent more than just technological innovation; they’re building the physical infrastructure of the AI age. As foundation models advance and training data from deployed robots create powerful feedback loops, we expect to see rapid capability improvements and expanding addressable markets. The winners in this space will be those who can navigate the unique challenges of physical AI, such as: 

  • Managing the complexity of real-world deployments
  • Building trusting relationships with enterprises concerning critical safety applications
  • Developing sustainable unit economics despite the high R&D costs facing the industry

As talent continues to migrate from leading AI labs to robotics startups, the next few years will separate those building genuine technological moats from those riding the wave of hype. If you’re a founder building in this space, we encourage you to connect with us. Contact us at robotics@bvp.com.